Lecture Outline for Quantitative Chemical Analysis

Note: bold-faced chapter numbers are new material – italicized should all be review!

Lecture Material

Assigned Readings

Exam

A.   The Nature of Quantitative Analysis

Chapter 0 (all)

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a.    general chemistry in the “real world”

Problems 0.1, 0.2, 0.4

b. syllabus overview and questions

B.   Measurement Tools & Calulations

Chapter 1 (1.1 thru 1.3)

a.   presenting results of calculations

Exercises 1.A (a), 1.B, 1.C; Problems 1.3, 1.5, 1.8, 1.11,

b.    solution calculations (M, mixing ratio, dilutions)

1.14, 1.15, 1.17–1.20, 1.24, 1.28, 1.29, 1.31, 1.33–1.35

c.     measurements of mass

Chapter 2 (all)

d. measurements of volume

Exercises 2.B, 2.C, 2.D, 2.E; Problems 2.5, 2.6,

2.7, 2.9, 2.10, 2.14, 2.15, 2.17, 2.21, 2.22

C.   Reintroduction of Equilibria - a Review!

Chapter 6  (6.1 thru 6.7)

a.    characterization and control of equilibria

Exercises 6.B, 6.C, 6.E, 6.F; Problems 6.4, 6.9, 6.14,

6.19, 6.20, 6.22, 6.24

D.   Gravimetric Analysis

Chapter 27 (27.1 thru 27.3)

a.    precipitation equilibria

Exercises 27.B, 27.C; Problems 27.2, 27.10, 27.11,

b. separation by precipitation

27.15, 27.18, 27.19, 27.26

c.    filtration and ignition

E.   Volumetric Analysis

Chapter 1 (1.4)

a.    stoichiometry & titration calculations

(revisit Problems 1.34-1.35, if necessary)

b.    standardization

Chapter 7 (7.1, 7.2, 7.4 thru 7.7)

c.    equivalence point vs. endpoint

Exercises 7.A, 7.B, 7.E; Problems 7.1, 7.2, 7.3, 7.4,

d.    blank titrations & back titrations

7.7, 7.8, 7.10, 7.11, 7.13, 7.16

F.    Acid/Base Equilibria & Titrations

Chapters 9-10 (9.1-9.4, 10.1)

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a.    weak acid/base dissociation

Exercises 9.B, 9.C, 9.D, 9.F; Problems 9.2, 9.3, 9.5,

b.    neutralization reactions

9.6, 9.11, 9.12, 9.13, 9.15, 9.18, 9.20, 9.21, 9.22, 9.23

c.    titration curve structure

Chapter 11 (11.1 thru 11.7)

d. indicators

Exercises 11.F, 11.G, 11.I(a), 11.J; Problems

e. primary standards

11.1, 11.2, 11.3, 11.4, 11.5, 11.10, 11.12, 11.13, 11.16,

11.18, 11.35, 11.36, 11.37, 11.40, 11.44, 11.46, 11.47

G.   Error Analysis & Statistics

Chapter 3 (all)

a.    meaning of significant figures

Exercise 3.A; Problems 3.7, 3.8 (but no gridlines),

b.    random vs. systematic error

3.9, 3.10, 3.11, 3.14, 3.15, 3.18, 3.19, 3.22

c.    absolute vs. relative error

d.    propagation of error

e.    standard deviation

H. Error Analysis of Standardized Values

Chapter 4 (4.1)

a.     std dev of sample populations

Exercise 4.C; Problems 4.1, 4.2, 4.3

b.     std dev of calibrated values

Chapter 4 (4.6 thru 4.8)

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I. Error Analysis of Sparse Data

Chapter 4 (4.2 thru 4.3)

a.   confidence limits and student's T calcs.

Exercises 4.A, 4.E, 4.G (you may use LINEST)

b.      comparison of measurements

Problems 4.8, 4.9, 4.11, 4.13, 4.14, 4.19, 4.20, 4.22, 4.23,

c.      statistical data exclusion

4.27, 4.32 (you may use Excel), 4.36

J.   Miscellaneous Error Issues

Chapter 5 (5.2 thru 5.4)

a.   reduction of systematic error

K.    Chromatographic Analysis

Chapter 23 (pp. 506-512)

a.    liquid/liquid extractions

Exercises 23.C; Problems 23.15, 23.16, 23.44(a, b, f)

b.    solvation/adsorption equilibria

c.    liquid chromatography

Chapter 25 ( 25.1 thru 25.2)

d.    chromatography calculations

Problems  25.1(a), 25.13(a & b), 25.15

e.    high-performance liquid chromatography

f.     gas chromatography

Chapter 24 (24.1 & 24.3)

g.    chromatography detectors

Problems 24.5, 24.10